Smart DNA

Smart DNA: Programming the Molecule of Life for Work and Play: Scientific American

  • DNA molecules can act as elementary logic gates analogous to the silicon-based gates of ordinary computers. Short strands of DNA serve as the gates’ inputs and outputs.
  • Ultimately, such gates could serve as dissolved “doctors”—sensing molecules such as markers on cells and jointly choosing how to respond.
  • Automata built from these DNA gates demonstrate the system’s computational abilities by playing an unbeatable game of tic-tac-toe.

Logic gates made of DNA could one day operate in your bloodstream, collectively making medical decisions and taking action. For now, they play a mean game of in vitro tic-tac-toe

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